Documentation

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How to use COSMIC²

• Accessing web server
• Data upload
• Checking job status
• Terminating existing job
• Downloading results
• Data management on COSMIC²

Data formats

All data is expected to be in the format of RELION STAR files with either particle stacks, micrographs, or movies.

Read more here.

Tools available

Preprocessing of cryo-EM data: motion correction, CTF estimation, & particle picking

• Preprocessing pipeline v0.1

RELION-3.0 tools: 

• 2D classification
• 3D initial model calculation
• 3D classification
• 3D refinement

Computing allocations

COSMIC2 is operated on the NSF-funded Comet supercomputer at the San Diego Supercomputer Center. As such, there are no costs associated with running jobs.

Read more here.