Model building tools on COSMIC2

We currently offer one tool & approach for building models into 3D density maps:

  • ModelAngelo – predict and build amino acid sequences into 3D reconstructions

In addition to building known sequences into 3D maps, ModelAngelo also allows you to predict a protein sequence given a 3D reconstruction. If you do this, then you will need to use the following tool to identify which proteins match the predicted sequence:

  • HHBlits – find protein sequences matching predicted sequence from ModelAngelo