Tools available on COSMIC²

A complete listing of tools on the gateway can be found here.

RELION

We offer individual RELION-3.1 commands for analyzing RELION-extracted particle stacks.

• 2D classification
• 3D initial model calculation
• 3D classification
• 3D refinement
• 3D multibody refinement

Data format conversion

• cryoSPARC to STAR files (csparc2star.py)

Validation & Analysis

• Efficiency (cryoEF)
• DeepEMhancer

3D heterogeneity analysis

• cryoDRGN